Mutagenesis Oxycodone hydrochloride was genotoxic in an in vitro mouse lymphoma assay inside the presence of metabolic activation. There was no proof of genotoxic probable in an in vitro bacterial reverse mutation assay (Salmonella typhimurium and Escherichia coli) or within an assay for chromosomal aberrations (in vivo mouse bone marrow micronucle
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